KEGG   Oryctolagus cuniculus (rabbit): 100009074
Entry
100009074         CDS       T03373                                 
Symbol
GAPDH
Name
(RefSeq) glyceraldehyde-3-phosphate dehydrogenase
  KO
K00134  glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00010  Glycolysis / Gluconeogenesis
ocu01100  Metabolic pathways
ocu01200  Carbon metabolism
ocu01230  Biosynthesis of amino acids
ocu04066  HIF-1 signaling pathway
ocu05010  Alzheimer disease
ocu05132  Salmonella infection
ocu05415  Diabetic cardiomyopathy
Module
ocu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ocu_M00002  Glycolysis, core module involving three-carbon compounds
ocu_M00003  Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100009074 (GAPDH)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    100009074 (GAPDH)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100009074 (GAPDH)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100009074 (GAPDH)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100009074 (GAPDH)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocu04131]
    100009074 (GAPDH)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ocu04147]
    100009074 (GAPDH)
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.12  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
     100009074 (GAPDH)
Membrane trafficking [BR:ocu04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    100009074 (GAPDH)
Exosome [BR:ocu04147]
 Exosomal proteins
  Proteins found in most exosomes
   100009074 (GAPDH)
SSDB
Motif
Pfam: Gp_dh_C Gp_dh_N LptD_N ADH_zinc_N
Other DBs
NCBI-GeneID: 100009074
NCBI-ProteinID: NP_001075722
UniProt: P46406
Structure
Position
8:complement(79061268..79065349)
AA seq 333 aa
MVKVGVNGFGRIGRLVTRAAFNSGKVDVVAINDPFIDLHYMVYMFQYDSTHGKFHGTVKA
ENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIIS
APSXDAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAIT
ATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
VDLTCRLEKAAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSATHSSTFDAGAGIA
LNDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
NT seq 1002 nt   +upstreamnt  +downstreamnt
atggtgaaggtcggagtgaacggatttggccgcattgggcgcctggtcaccagggctgct
tttaactctggcaaagtggatgttgtcgccatcaatgatccattcattgacctccactac
atggtctacatgttccagtatgattccacccacggcaagttccacggcacggtcaaggct
gagaacgggaagctggtcatcaacgggaaggccatcaccatcttccaggagcgagatccc
gccaacatcaagtggggtgatgctggtgccgagtacgtggtggaatccactggcgtcttc
accaccatggagaaggccggggctcatttgaagggcggagccaaaagggtcatcatctca
gccccctcckccgatgcccccatgtttgtgatgggcgtgaaccacgagaagtatgacaac
tctctcaagattgtcagcaacgcatcctgcaccaccaactgcttagcccccctggccaag
gtcatccacgaccacttcggcattgtggaggggctcatgaccacggtgcacgccatcact
gccacccagaagaccgtggacgggccctctgggaagctgtggcgtgacggccgcggggcc
gcccagaacatcatccctgcctccactggcgctgccaaggccgtgggcaaggtcatcccc
gagctgaacgggaaactcactggcatggccttccgtgtgcccacccccaacgtgtcggtc
gtggacctgacctgccgcctggagaaagctgctaagtatgacgacatcaagaaggtggtg
aagcaggcatccgagggccccctgaagggcatcctgggctacaccgaggaccaggtcgtc
tcctgcgacttcaacagtgccacccactcctctaccttcgatgctggggctggcattgcc
ctcaatgaccactttgtgaagctcatttcctggtatgacaacgaatttggctacagcaac
agggtggtggacctcatggtccacatggcctccaaggagtaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (14)   
   KEGG PATHWAY (8)   
   KEGG MODULE (6)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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